The most common pathogens associated with sepsis and septic shock in the United States are gram-positive bacteria, including streptococcal pneumonia and Enterococcus. Septic shock is a subset of sepsis with severe circulatory, cellular, and metabolic abnormalities resulting in tissue hypoperfusion manifested as hypotension which requires vasopressor therapy and elevated lactate levels (more than 2 mmol/L) Sepsis is defined as life-threatening organ dysfunction resulting from dysregulated host response to infection. Undifferentiated shock means that the diagnosis of shock has been made however, the underlying etiology has not been uncovered.Ĭharacterized by peripheral vasodilatation. The wide range of etiologies can contribute to each of these categories and are manifested by the final outcome of shock. There are mainly four broad categories of shock: distributive, hypovolemic, cardiogenic, and obstructive. Shock is the final manifestation of a complex list of etiologies and could be fatal without timely management. It is a life-threatening condition of circulatory failure and most commonly manifested as hypotension (systolic blood pressure less than 90 mm Hg or MAP less than 65 mmHg). Shock is characterized by decreased oxygen delivery and/or increased oxygen consumption or inadequate oxygen utilization leading to cellular and tissue hypoxia.

System shock 2 the many sing to us